Antimalarial agent 3

• Description:

  Antimalarial agent 3 shows nanomolar antiplasmodial activity (IC50 = 0.035 μM) and has a very high selectivity index with respect to mammalian cells.

• UNSPSC:

  12352005

• Target:

  Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/antimalarial-agent-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C1=CC=C(C2=NN=C(C3CC(Br)=NO3)O2)C=C1)(C)C

• Molecular Formula:

  C15H16BrN3O2

• Molecular Weight:

  350.21

• References & Citations:

  [1]Galbiati A, et al. Development of Potent 3-Br-isoxazoline-Based Antimalarial and Antileishmanial Compounds. ACS Med Chem Lett. 2021 Oct 13;12 (11) :1726-1732.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Plasmodium

• CAS Number:

  3033386-12-5