Antimalarial agent 3

CAT: 0804-HY-132906Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-132906Size:1 Each
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Description
Antimalarial agent 3 shows nanomolar antiplasmodial activity (IC50 = 0.035 μM) and has a very high selectivity index with respect to mammalian cells.
CAS Number
[3033386-12-5]
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antimalarial-agent-3.html
Solubility
10 mM in DMSO
Smiles
CC(C1=CC=C(C2=NN=C(C3CC(Br)=NO3)O2)C=C1)(C)C
Molecular Formula
C15H16BrN3O2
Molecular Weight
350.21
References & Citations
[1]Galbiati A, et al. Development of Potent 3-Br-isoxazoline-Based Antimalarial and Antileishmanial Compounds. ACS Med Chem Lett. 2021 Oct 13;12 (11) :1726-1732.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Plasmodium

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