Antimalarial agent 3

• Description :

  Antimalarial agent 3 shows nanomolar antiplasmodial activity (IC50 = 0.035 μM) and has a very high selectivity index with respect to mammalian cells.

• UNSPSC :

  12352005

• Target :

  Parasite

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/antimalarial-agent-3.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC(C1=CC=C(C2=NN=C(C3CC(Br)=NO3)O2)C=C1)(C)C

• Molecular Formula :

  C15H16BrN3O2

• Molecular Weight :

  350.21

• References & Citations :

  [1]Galbiati A, et al. Development of Potent 3-Br-isoxazoline-Based Antimalarial and Antileishmanial Compounds. ACS Med Chem Lett. 2021 Oct 13;12 (11) :1726-1732.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Plasmodium

• CAS Number :

  [3033386-12-5]