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Antimalarial agent 18

CAT: 0931-T72416-01Size: 25 mgDry Ice: NoHazardous: No
CAT#: T72416-01Size: 25 mg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Parasite|||Others
Related Pathways
Microbiology/Virology|||Others
Bioactivity
Antimalarial agent 18, a powerful antimalarial compound characterized by its electronic, highly lipophilic, and siderophoric properties, falls within the acyloxymethyl series, acting as a fosmidomycin surrogate. It effectively inhibits the non-mevalonate isoprenoid biosynthesis pathway by targeting the IspC enzyme. This compound demonstrates significant inhibitory activity against P. falciparum (IC50 = 50 nM) and A. baumanii (IC50 = 390 nM) .
Smiles
CCCCCCCC(=O)OCOP(=O)(CCCC(=O)N(C)O)OCOC(=O)CCCCCCC
Molecular Formula
C23H44NO9P
Molecular Weight
509.57
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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