Antimalarial agent 9

• Description:

  Antimalarial agent 9 (Compound 11) is a potent antimalarial agent. Antimalarial agent 9 is a quinoline-imidazole derivative compound. Antimalarial agent 9 exhibits significant antimalarial efficacy in-vitro against both CQ-sensitive (IC50-0.14 μM) and MDR strain (IC50-0.41 μM) with minimal cytotoxicity and high selectivity[1].

• UNSPSC:

  12352005

• Target:

  Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/antimalarial-agent-9.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=NC2=CC=C(C=C2C=C1C(N3C=CN=C3)C4=CC(C(C)(C)C)=C(C(C(C)(C)C)=C4)O)Br

• Molecular Formula:

  C28H32BrN3O2

• Molecular Weight:

  522.48

• References & Citations:

  [1]Roy D, et al. Synthesis, biological evaluation, Structure - Activity relationship studies of quinoline-imidazole derivatives as potent antimalarial agents. Bioorg Chem. 2022;121:105671.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Plasmodium

• CAS Number:

  [2914224-54-5]