Antimalarial agent 9

• Description :

  Antimalarial agent 9 (Compound 11) is a potent antimalarial agent. Antimalarial agent 9 is a quinoline-imidazole derivative compound. Antimalarial agent 9 exhibits significant antimalarial efficacy in-vitro against both CQ-sensitive (IC50-0.14 μM) and MDR strain (IC50-0.41 μM) with minimal cytotoxicity and high selectivity[1].

• UNSPSC :

  12352005

• Target :

  Parasite

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/antimalarial-agent-9.html

• Solubility :

  10 mM in DMSO

• Smiles :

  COC1=NC2=CC=C(C=C2C=C1C(N3C=CN=C3)C4=CC(C(C)(C)C)=C(C(C(C)(C)C)=C4)O)Br

• Molecular Formula :

  C28H32BrN3O2

• Molecular Weight :

  522.48

• References & Citations :

  [1]Roy D, et al. Synthesis, biological evaluation, Structure - Activity relationship studies of quinoline-imidazole derivatives as potent antimalarial agents. Bioorg Chem. 2022;121:105671.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Plasmodium

• CAS Number :

  [2914224-54-5]