Antimalarial agent 9

Antimalarial agent 9

• CAS Number: 9007-83-4
• UNSPSC Description: Antimalarial agent 9 (Compound 11) is a potent antimalarial agent. Antimalarial agent 9 is a quinoline-imidazole derivative compound. Antimalarial agent 9 exhibits significant antimalarial efficacy in-vitro against both CQ-sensitive (IC50-0.14 μM) and MDR strain (IC50-0.41 μM) with minimal cytotoxicity and high selectivity[1].
• Target Antigen: Parasite
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/antimalarial-agent-9.html
• Solubility: 10 mM in DMSO
• Smiles: COC1=NC2=CC=C(C=C2C=C1C(N3C=CN=C3)C4=CC(C(C)(C)C)=C(C(C(C)(C)C)=C4)O)Br
• Molecular Weight: 522.48
• References & Citations: [1]Roy D, et al. Synthesis, biological evaluation, Structure - Activity relationship studies of quinoline-imidazole derivatives as potent antimalarial agents. Bioorg Chem. 2022;121:105671.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported