Antimalarial agent 15

• Description :

  Antimalarial agent 15 (Compound 4e) is a parasite inhibitor. Antimalarial agent 15 shows antimalarial activity, and can inhibit P. falciparum 3D7 parasite growth (IC50=20 nM) [1].

• UNSPSC :

  12352005

• Target :

  Parasite

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/antimalarial-agent-15.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CCCCC1=CC(OC2=C1C(OCC(N3CC4=C(C5=C(N4)C=CC=C5)C[C@H]3C(OC)=O)=O)=CC(C)=C2)=O

• Molecular Formula :

  C29H30N2O6

• Molecular Weight :

  502.56

• References & Citations :

  [1]Nobuo Cho, et al. New antimalarials identified by a cell-based phenotypic approach: Structure-activity relationships of 2,3,4,9-tetrahydro-1H-β-carboline derivatives possessing a 2- ((coumarin-5-yl) oxy) alkanoyl moiety. Bioorg Med Chem. 2022 Jul 15;66:116830.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Plasmodium

• CAS Number :

  [956928-33-9]