Antimalarial agent 15

• UNSPSC Description:

  Antimalarial agent 15 (Compound 4e) is a parasite inhibitor. Antimalarial agent 15 shows antimalarial activity, and can inhibit P. falciparum 3D7 parasite growth (IC50=20 nM)[1].

• Target Antigen:

  Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/antimalarial-agent-15.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCCC1=CC(OC2=C1C(OCC(N3CC4=C(C5=C(N4)C=CC=C5)C[C@H]3C(OC)=O)=O)=CC(C)=C2)=O

• Molecular Weight:

  502.56

• References & Citations:

  [1]Nobuo Cho, et al. New antimalarials identified by a cell-based phenotypic approach: Structure-activity relationships of 2,3,4,9-tetrahydro-1H-β-carboline derivatives possessing a 2-((coumarin-5-yl)oxy)alkanoyl moiety. Bioorg Med Chem. 2022 Jul 15;66:116830.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4