Antimalarial agent 31

• UNSPSC Description:

  Antimalarial agent 31 (compound 7k) is an orally active Plasmodium falciparum aspartic protease plasmepsin X (PMX) inhibitor[1].

• Target Antigen:

  Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/antimalarial-agent-31.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@@H]([C@@H](NC(C1=CC=CC(C(N(CCC)CCCCC2)=O)=C1)=O)CC3=CC=CC2=C3)CNC(C)(C)C4=CC=CC(OC)=C4

• Molecular Weight:

  585.78

• References & Citations:

  [1]Vadims Kovada, et al. Macrocyclic Peptidomimetic Plasmepsin X Inhibitors with Potent In Vitro and In Vivo Antimalarial Activity. J Med Chem. 2023 Aug 10;66(15):10658-10680.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4