Antimalarial agent 31

• Description :

  Antimalarial agent 31 (compound 7k) is an orally active Plasmodium falciparum aspartic protease plasmepsin X (PMX) inhibitor[1].

• UNSPSC :

  12352005

• Target :

  Parasite

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/antimalarial-agent-31.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O[C@@H]([C@@H](NC(C1=CC=CC(C(N(CCC)CCCCC2)=O)=C1)=O)CC3=CC=CC2=C3)CNC(C)(C)C4=CC=CC(OC)=C4

• Molecular Formula :

  C36H47N3O4

• Molecular Weight :

  585.78

• References & Citations :

  [1]Vadims Kovada, et al. Macrocyclic Peptidomimetic Plasmepsin X Inhibitors with Potent In Vitro and In Vivo Antimalarial Activity. J Med Chem. 2023 Aug 10;66 (15) :10658-10680.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [3033682-50-4]