Antimalarial agent 31

CAT: 0804-HY-155130Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-155130Size:1 Each
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Description
Antimalarial agent 31 (compound 7k) is an orally active Plasmodium falciparum aspartic protease plasmepsin X (PMX) inhibitor[1].
CAS Number
[3033682-50-4]
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antimalarial-agent-31.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]([C@@H](NC(C1=CC=CC(C(N(CCC)CCCCC2)=O)=C1)=O)CC3=CC=CC2=C3)CNC(C)(C)C4=CC=CC(OC)=C4
Molecular Formula
C36H47N3O4
Molecular Weight
585.78
References & Citations
[1]Vadims Kovada, et al. Macrocyclic Peptidomimetic Plasmepsin X Inhibitors with Potent In Vitro and In Vivo Antimalarial Activity. J Med Chem. 2023 Aug 10;66 (15) :10658-10680.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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