Mt KARI-IN-2

CAT: 0931-T61570-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T61570-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2413974-52-2

Target

Others, Antibacterial

Related Pathways

Microbiology/Virology, Others

Bioactivity

Mt KARI-IN-2 (compound 5b) is a highly effective inhibitor of Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI), with a Ki value of 2.02 μM. It also inhibits Mtb H37Rv with a MIC value of 0.78 μM and demonstrates low cytotoxicity, as indicated by a HEK IC50 greater than 86 μg/mL [1].

Smiles

N(C(NC1=CC=C(OC)C=C1)=S)C=2SC(=NN2)C=3OC(N(=O)=O)=CC3

Molecular Formula

C14H11N5O4S2

Molecular Weight

377.4

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
MBS5804273	Mt KARI-IN-2
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HY-171962A-01	KARI 201 (hydrochloride)
MBS5804770	Mt KARI-IN-5
HY-146300	Mt KARI-IN-4
GTR19263463-01	KARI 201 hydrochloride
AS15 2879	KARI \| Ketol-acid reductoisomerase
PC1003049-01	2,2,2-Trifluoroethyl 2,2,2-trichloroacetate
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