Mt KARI-IN-1
CAT:
804-HY-146298
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Mt KARI-IN-1
- CAS Number: 2987760-64-3
- UNSPSC Description: Mt KARI-IN-1 (Lead compound) is a potent Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI) inhibitor with a Ki value of 3.06 μM[1].
- Target Antigen: Bacterial
- Type: Reference compound
- Related Pathways: Anti-infection
- Applications: COVID-19-immunoregulation
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/mt-kari-in-1.html
- Solubility: 10 mM in DMSO
- Smiles: COC1=CC=C(C=C1)NC(NC2=NN=C(S2)C3=CC=C(S3)[N+]([O-])=O)=O
- Molecular Weight: 377.40
- References & Citations: [1]Krishna VS, et al. Design and development of ((4-methoxyphenyl)carbamoyl) (5-(5-nitrothiophen-2-yl)-1,3,4-thiadiazol-2-yl)amide analogues as Mycobacterium tuberculosis ketol-acid reductoisomerase inhibitors. Eur J Med Chem. 2020;193:112178.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported