2-MT-63

CAT: 0931-MF-0056055-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0056055-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
870225-11-9
Target
Others|||Tie-2
Related Pathways
Others|||Tyrosine Kinase/Adaptors
Bioactivity
2-MT 63 is a novel TIE-2 kinase inhibitor that demonstrates unique and improved kinase selectivity compared to other inhibitors known to interact with TIE-2. 2-MT 63 has a good kinase selectivity profile in enzyme assays with >30-fold selectivity (typically much greater) against the tested kinases. Importantly, the profile includes selectivity against other targets of relevance for angiogenesis (KDR, PDGFR, EPHB4) .
Smiles
O(C1=C(C=CC=N1)C=2N=C(NC)N=CN2)C3=CC(C(NC4=C(N(CCCN(C)C)C)C=CC(C(F)(F)F)=C4)=O)=C(F)C=C3
Molecular Formula
C29H30F4N8O2
Molecular Weight
598.59
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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