MT-1207

• Target:

  5-HT Receptor|||Adrenergic Receptor

• Related Pathways:

  Neuroscience|||GPCR/G Protein

• Bioactivity:

  MT-1207 is a selective antagonist of adrenergic ?1 and 5-HT2A receptors with oral activity. It exhibits IC50 values of <0.1 nM for ?1A, 0.15 nM for ?1B, 1.40 nM for ?1D, and 0.27 nM for 5-HT2A. In the 2K2C rat model, MT-1207 effectively reduces blood pressure (BP) without impairing renal function. As a multitarget inhibitor, MT-1207 has potential for research in vasodilation.

• Smiles:

  Cl.N1=NN (C=2C=CC=CC12) CCCCN3CCN (C4=NSC=5C=CC=CC54) CC3

• Molecular Formula:

  C21H25ClN6S

• Molecular Weight:

  428.98

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1610794-70-1