MT-1207

CAT: 0931-T88520-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T88520-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1610794-70-1
Target
5-HT Receptor|||Adrenergic Receptor
Related Pathways
Neuroscience|||GPCR/G Protein
Bioactivity
MT-1207 is a selective antagonist of adrenergic ?1 and 5-HT2A receptors with oral activity. It exhibits IC50 values of <0.1 nM for ?1A, 0.15 nM for ?1B, 1.40 nM for ?1D, and 0.27 nM for 5-HT2A. In the 2K2C rat model, MT-1207 effectively reduces blood pressure (BP) without impairing renal function. As a multitarget inhibitor, MT-1207 has potential for research in vasodilation.
Smiles
Cl.N1=NN(C=2C=CC=CC12)CCCCN3CCN(C4=NSC=5C=CC=CC54)CC3
Molecular Formula
C21H25ClN6S
Molecular Weight
428.98
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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