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Mt KARI-IN-5

CAT: 0931-T62081-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T62081-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2413974-69-1
Target
Antibacterial, Others
Related Pathways
Others, Microbiology/Virology
Bioactivity
Mt KARI-IN-5 (compound 6c) was a potent inhibitor of Mycobacterium tuberculosis ketohydrin reductase I (MtbKARI) (Ki: 4.72 μM), exhibited inhibition of MtbH37Rv activity with a MIC value of 1.56 μM, showed low cytotoxicity, and had an IC50 value for HEK greater than 64 μg/mL.
Smiles
N(S(=O)(=O)C1=CC=C(C(C)=O)C=C1)C=2SC(=NN2)C=3SC(N(=O)=O)=CC3
Molecular Formula
C14H10N4O5S3
Molecular Weight
410.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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