XL-784 free base

• Target:

  MMP|||Others

• Related Pathways:

  Others|||Proteases/Proteasome

• Bioactivity:

  XL-784 free base is a selective inhibitor of matrix metalloproteinases (MMP) with IC50 values of ~1900, 0.81, 120, 10.8, 18, and 0.56 nM for MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, and MMP-13, respectively.

• Smiles:

  S(=O)(=O)(N1C(C(NO)=O)CN(C(OCCOC)=O)CC1)C2=CC(F)=C(OC3=CC=C(Cl)C=C3)C(F)=C2

• Molecular Formula:

  C21H22ClF2N3O8S

• Molecular Weight:

  549.93

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1356992-21-6