XL-784

CAT: 0931-T13358-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
CAT#:0931-T13358-01Size:1 mL - 10 mM (in DMSO)
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1224964-36-6
Target
MMP
Related Pathways
Proteases/Proteasome
Bioactivity
XL-784 is a selective inhibitor of matrix metalloproteinases (MMPs) with IC50 values of approximately 1900, 0.81, 120, 10.8, 18, and 0.56 nM for MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, and MMP-13, respectively. XL-784 demonstrates potential in a broad range of cancer research applications due to its capability to modulate extracellular matrix remodeling, tumor invasion, and metastasis.
Smiles
O=C(N1CCN(S(=O)(C2=CC(F)=C(C(F)=C2)OC3=CC=C(C=C3)Cl)=O)C(C1)C(N[O-])=O)OCCOC.O=C(N4CCN(S(=O)(C5=CC(F)=C(C(F)=C5)OC6=CC=C(C=C6)Cl)=O)C(C4)C(N[O-])=O)OCCOC.[Mg+2]
Molecular Formula
C42H42Cl2F4MgN6O16S2
Molecular Weight
1122.15
Shipping Conditions
Cool pack
Storage Temperature
-20°C