BPH-1358 free base

• Target:

  Others|||Antibacterial

• Related Pathways:

  Microbiology/Virology|||Others

• Bioactivity:

  BPH-1358 (NSC50460) free base is a potent human undecaprenyl diphosphate synthase (UPPS) and farnesyl diphosphate synthase (FPPS) inhibitor (IC50s: 110 nM and 1.8 ?M) and is active against S. aureus in vitro (MIC ~250 ng/mL) .

• Smiles:

  N(C(=O)C1=CC=C(C=C1)C2=CC=C(C(NC3=CC(=CC=C3)C=4NCCN4)=O)C=C2)C=5C=C(C=CC5)C=6NCCN6

• Molecular Formula:

  C32H28N6O2

• Molecular Weight:

  528.6

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  801985-13-7