BPH-1358 mesylate

• Target :

  Others|||Antibacterial

• Related Pathways :

  Others|||Microbiology/Virology

• Bioactivity :

  BPH-1358 mesylate (NSC50460 mesylate), a highly effective inhibitor of both human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS), exhibits IC50 values of 1.8 ?M and 110 nM, respectively. Additionally, this compound demonstrates potent in vitro activity against S. aureus, with a minimum inhibitory concentration (MIC) approximately 250 ng/mL.

• Smiles :

  CS(=O)(=O)O.CS(=O)(=O)O.C1CN=C(N1)C2=CC(=CC=C2)NC(=O)C3=CC=C(C=C3)C4=CC=C(C=C4)C(=O)NC5=CC=CC(=C5)C6=NCCN6

• Molecular Formula :

  C34H36N6O8S2

• Molecular Weight :

  720.82

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C