AFP464 free base

CAT: 0931-T10258-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T10258-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

468719-52-0

Target

HIF/HIF Prolyl-Hydroxylase, HIF

Related Pathways

Metabolism, Angiogenesis, Chromatin/Epigenetic

Bioactivity

AFP464 (NSC710464) free base is an active HIF-1α inhibitor (IC50: 0.25 μM) and a potent aryl hydrocarbon receptor (AhR) activator.

Smiles

FC1=C2C(C(=O)C=C(O2)C3=CC(F)=C(NC([C@H](CCCCN)N)=O)C=C3)=C(N)C(F)=C1C

Molecular Formula

C22H23F3N4O3

Molecular Weight

448.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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