AFP464 free base

• Target :

  HIF/HIF Prolyl-Hydroxylase|||HIF

• Related Pathways :

  Metabolism|||Angiogenesis|||Chromatin/Epigenetic

• Bioactivity :

  AFP464 (NSC710464) free base is an active HIF-1? inhibitor (IC50: 0.25 ?M) and a potent aryl hydrocarbon receptor (AhR) activator.

• Smiles :

  FC1=C2C(C(=O)C=C(O2)C3=CC(F)=C(NC([C@H](CCCCN)N)=O)C=C3)=C(N)C(F)=C1C

• Molecular Formula :

  C22H23F3N4O3

• Molecular Weight :

  448.44

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  468719-52-0