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BMS-813160

CAT: 0804-HY-109593-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-109593-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BMS-813160 is a potent and selective CCR2/5 dual antagonist. BMS-813160 binds with CCR2 and CCR5 with IC50s of 6.2 and 3.6 nM, respectively. BMS-813160 can be used for the research of inflammation[1][2].
CAS Number
1286279-29-5
UNSPSC
12352005
Hazard Statement
H315, H317, H318, H334, H335, H341, H361, H370, H413
Target
CCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Endocrinology; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/BMS-813160.html
Purity
99.82
Solubility
DMSO : 25 mg/mL (ultrasonic; warming) |Ethanol : 100 mg/mL (ultrasonic)
Smiles
CC(N[C@H]1[C@@H](N2C([C@@H](NC3=NC=NC4=CC(C(C)(C)C)=NN43)CC2)=O)CC[C@@H](NC(C)(C)C)C1)=O
Molecular Formula
C25H40N8O2
Molecular Weight
484.64
Precautions
H315, H317, H318, H334, H335, H341, H361, H370, H413
References & Citations
[1]Norman P. et al. A dual CCR2/CCR5 chemokine antagonist, BMS-813160? Evaluation of WO2011046916. Expert Opin Ther Pat. 2011 Dec;21 (12) :1919-24.|[2]Cherney RJ, et al. BMS-813160: A Potent CCR2 and CCR5 Dual Antagonist Selected as a Clinical Candidate. ACS Med Chem Lett. 2021 Oct 15;12 (11) :1753-1758.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
CCR2; CCR5

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Alternative Products

CatalogName
BA5245-5.1BMS-813160
BB164193-01BMS 813160
A17040-50BMS-813160 50mg
A17040-5BMS-813160 5mg
A17040-1BMS-813160 1mg
A17040-500BMS-813160 500mg
A17040-100BMS-813160 100mg
A17040-25BMS-813160 25mg

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