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BMS-748730

CAT: 0804-HY-111158Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-111158Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BMS-748730 is an oral tyrosine kinase inhibitor. BMS-748730 inhibits tyrosine kinase activity by competing with the ATP binding site of the tyrosine kinase, which prevents the kinase from phosphorylating the substrate protein, thereby inhibiting signaling pathways associated with cell proliferation and tumor growth. BMS-748730 can be used in the study of certain types of cancer, including chronic myeloid leukemia (CML) [1].
CAS Number
910297-57-3
UNSPSC
12352005
Target
C-Met/HGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bms-748730.html
Smiles
O=C(C1=CN=C(NC2=CC(N3CCN(CC3)CCO)=NC(C)=N2)S1)NC4=C(C)C=C(O)C=C4Cl
Molecular Formula
C22H26ClN7O3S
Molecular Weight
504.00
References & Citations
[1]Erp, P. H. van. Clinical pharmacology of the tyrosine kinase inhibitors imatinib and sunitinib. Leiden University Medical Center (LUMC), Leiden University. 2009, December 16.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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