Thalidomide-5-methyl

• UNSPSC Description:

  Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein[1].

• Target Antigen:

  Apoptosis; Autophagy; Ligands for E3 Ligase

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;Autophagy;PROTAC

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/thalidomide-5-methyl.html

• Smiles:

  O=C1NC(C(CC1)N2C(C3=CC=C(C)C=C3C2=O)=O)=O

• Molecular Weight:

  272.26

• References & Citations:

  [1]George W. Muller, et al. Substituted 2-(2,6 dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing TNFα levels. Patent US5874448A.

• Shipping Conditions:

  Room Temperature

• CAS Number:

  40313-92-6