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Thalidomide-5-OH

CAT: 0931-T9291-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
CAT#:0931-T9291-01Size:1 mL - 10 mM (in DMSO)
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
64567-60-8
Target
Autophagy|||Ligand for E3 Ligase|||Apoptosis
Related Pathways
PROTAC|||Apoptosis|||Autophagy
Purity
0.9894
Bioactivity
Thalidomide-5-OH (2- (2,6-dioxopiperidin-3-yl) -5-hydroxyisoindoline-1,3-dione) is the Thalidomide-based cereblon ligand that used in the recruitment of CRBN protein. It can be connected to the ligand for protein by a linker to form PROTAC.
Smiles
O=C1N(C(=O)C=2C1=CC(O)=CC2)C3C(=O)NC(=O)CC3
Molecular Formula
C13H10N2O5
Molecular Weight
274.23
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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