Thalidomide-5-OH

• Target:

  Autophagy|||Ligand for E3 Ligase|||Apoptosis

• Related Pathways:

  PROTAC|||Apoptosis|||Autophagy

• Purity:

  0.9894

• Bioactivity:

  Thalidomide-5-OH (2- (2,6-dioxopiperidin-3-yl) -5-hydroxyisoindoline-1,3-dione) is the Thalidomide-based cereblon ligand that used in the recruitment of CRBN protein. It can be connected to the ligand for protein by a linker to form PROTAC.

• Smiles:

  O=C1N(C(=O)C=2C1=CC(O)=CC2)C3C(=O)NC(=O)CC3

• Molecular Formula:

  C13H10N2O5

• Molecular Weight:

  274.23

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  64567-60-8