Thalidomide-5-propoxyethanamine

• UNSPSC Description:

  Thalidomide-5-propoxyethanamine is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein[1].

• Target Antigen:

  Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;Autophagy;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/thalidomide-5-propoxyethanamine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1NC(C(CC1)N2C(C3=CC=C(CCCOCCN)C=C3C2=O)=O)=O

• Molecular Weight:

  359.38

• References & Citations:

  [1]Mainolfi, Nello, et al. IRAK DEGRADERS AND USES THEREOF. Patent US20190192668A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2357107-60-7