Thalidomide-5-carbaldehyde

CAT: 0931-T206143-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T206143-01Size:10 mg
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CAS Number
1447701-63-4
Target
Ligand for E3 Ligase
Related Pathways
PROTAC
Bioactivity
Thalidomide-5-carbaldehyde is an aldehyde-containing analogue of Thalidomide. Thalidomide recruits E3 ligase for ubiquitination, leading to proteolysis of target proteins. The aldehyde group exhibits high reactivity towards amine nucleophiles through reactions such as reductive amination.
Smiles
O=CC1=CC=C2C(=O)N(C(=O)C2=C1)C3C(=O)NC(=O)CC3
Molecular Formula
C14H10N2O5
Molecular Weight
286.24
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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