LSD1-IN-36

CAT: 0804-HY-168504Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-168504Size:1 Each
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Description
LSD1-IN-36 is a potent LSD1 inhibitor with an IC50 value of 0.8 nM. LSD1-IN-36 induces apoptosis and arrests the cell cycle. LSD1-IN-36 shows antitumor activity[1].
UNSPSC
12352005
Target
Apoptosis; Histone Demethylase
Type
Reference compound
Related Pathways
Apoptosis; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lsd1-in-36.html
Smiles
CC1COCC(N1S(=O)(C2=CC(C(N/N=C3CCC4=C(C=CC(O)=C4\3)O)=O)=CC=C2)=O)C
Molecular Formula
C22H25N3O6S
Molecular Weight
459.52
References & Citations
[1]Wei Ai, et al. Synthesis, optimization and antitumor activity evaluation of sulfonyl benzoyl hydrazide derivatives as novel human LSD1 inhibitors. Bioorg Med Chem Lett. 2024 Oct 9:114:129982.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
KDM1/LSD1

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