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LSD1-IN-32

CAT: 0804-HY-161869Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161869Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LSD1-IN-32 (compound 11e) is a potent LSD1 inhibitor with an IC50 value of 0.99 µM. LSD1-IN-32 inhibits RANKL-induced osteoclastogenesis, bone resorption and F-actin belt formation. LSD1-IN-32 has the potential for the research of osteoporosis[1].
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/lsd1-in-32.html
Smiles
O=C(N1CCC(CN[C@H]2[C@H](C3=CC=CC=C3)C2)CC1)/C=C/C4=CC=C(O[Si](C)(C(C)(C)C)C)C(O[Si](C)(C(C)(C)C)C)=C4
Molecular Formula
C36H56N2O3Si2
Molecular Weight
621.01
References & Citations
[1]Chen Z, et al. Discovery of TCP- (MP) -caffeic acid analogs as a new class of agents for treatment of osteoclastic bone loss. Bioorg Chem. 2024 Sep;150:107603.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported