LSD1-IN-22

• Description :

  LSD1-IN-22 is a potent Lysine-specific demethylase 1 (LSD1) inhibitor with a Ki value of 98 nM. LSD1-IN-22 has anti-proliferative activity against certain cancer cells[1].

• UNSPSC :

  12352005

• Target :

  Histone Demethylase

• Type :

  Reference compound

• Related Pathways :

  Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/lsd1-in-22.html

• Solubility :

  10 mM in DMSO

• Smiles :

  N[C@H]1[C@H](C2=CC(F)=C(Br)C=C2F)C1

• Molecular Formula :

  C9H8BrF2N

• Molecular Weight :

  248.07

• References & Citations :

  [1]Hideaki Niwa, et al. Structure-Activity Relationship and In Silico Evaluation of cis- and trans-PCPA-Derived Inhibitors of LSD1 and LSD2. ACS Medicinal Chemistry Letters Article ASAP.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  KDM1/LSD1

• CAS Number :

  [2821068-05-5]