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LSD1-IN-31

CAT: 0804-HY-161849Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161849Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LSD1-IN-31 (compound 11e) can directly bind to LSD1/CoREST complex to reduce LSD1 demethylation enzymatic activity. LSD1-IN-31 inhibits LSD1 demethylation activity and influences its downstream IκB/NF-κB signaling pathway. LSD1-IN-31 inhibits osteoclastic bone loss in vitro and in vivo. LSD1-IN-31 can be used for osteoporosis research[1].
UNSPSC
12352005
Target
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/lsd1-in-31.html
Smiles
O=C(N1CCC(CN[C@H]2[C@H](C3=CC=CC=C3)C2)CC1)/C=C/C4=CC(O[Si](C)(C)C(C)(C)C)=C(O[Si](C)(C)C(C)(C)C)C=C4.Cl
Molecular Formula
C36H57ClN2O3Si2
Molecular Weight
657.47
References & Citations
[1]Chen Z, et al. Discovery of TCP- (MP) -caffeic acid analogs as a new class of agents for treatment of osteoclastic bone loss. Bioorg Chem. 2024 Sep;150:107603.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
KDM1/LSD1

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