LSD1-IN-14

CAT: 0804-HY-145861Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-145861Size:1 Each
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Description
LSD1-IN-14 is a potent and selective LSD1 inhibitor (IC50=0.89 μM) . LSD1-IN-14 can significantly inhibit the proliferation of A549 and THP-1 cells and induce the apoptosis of tumor cells[1].
CAS Number
[2698340-11-1]
UNSPSC
12352005
Target
Apoptosis; Histone Demethylase
Type
Reference compound
Related Pathways
Apoptosis; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lsd1-in-14.html
Solubility
10 mM in DMSO
Smiles
CN(CCN(C1=CC=C(C=C1)NC2=NC=C(C=N2)C3=CC=C(C=C3)F)C)C
Molecular Formula
C21H24FN5
Molecular Weight
365.45
References & Citations
[1]Wang X, et al. Design, synthesis and biological evaluation of 2-aminopyrimidine-based LSD1 inhibitors. Bioorg Chem. 2022;121:105699.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
KDM1/LSD1

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