Products for Research Use Only
RegisterLogin

LSD1-IN-42

CAT: 0804-HY-172809Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-172809Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
LSD1-IN-42 (Compound 7ae) is an orally active LSD1 inhibitor that potently inhibits LSD1 activity (IC50 = 0.08 μM) . LSD1-IN-42 downregulates PD-L1 expression and enhances T cell-mediated tumor killing effects. LSD1-IN-42 demonstrates significant anti-gastric cancer activity by inhibiting tumor cell invasion and migration[1].
UNSPSC
12352101
Target
Histone Demethylase; PD-1/PD-L1
Related Pathways
Epigenetics; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Smiles
O=C1OCC(C1=C)C(O)C2=CN(C3=C2C=C(C=C3)Cl)S(=O)(C4=CC=C(C([N+]([O-])=O)=C4)N(C)C)=O
Molecular Formula
C22H20ClN3O7S
Molecular Weight
505.93
References & Citations
[1]Zhang H, et al. The Exploration of Indole-Based LSD1-Targeted Inhibitors for Enhanced Immune Response in Gastric Cancer via the PD-L1/PD-1 Axis. J Med Chem. 2025 Apr 21.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
KDM1/LSD1

Related Products

CatalogName
HY-173123LSD1-IN-40
HY-178826LSD1-IN-45
HY-144758LSD1-IN-17
HY-161849LSD1-IN-31
HY-161869LSD1-IN-32
HY-151191LSD1-IN-22
HY-145861LSD1-IN-14
HY-160191-01LSD1-IN-30
HY-163859LSD1-IN-33
HY-160183LSD1-IN-29

Alternative Products

CatalogName
T206648-01LSD1-IN-42
bs-60179C-01GSK-LSD1 --- LSD1 Inhibitor
bs-66045C-01LSD1-C76, LSD1 Inhibitor
MBS8565299-01LSD1
GTR18868076-01Human Protein LSD1 (LSD1) ELISA Kit
MBS1217282-01Recombinant Arabidopsis thaliana Protein LSD1 (LSD1)
BA4801-5.1LSD1-IN-24
BA4809-5LSD1-IN-27
T210222-01LSD1-IN-32
T89469-01LSD1-IN-31

Popular Products