Products for Research Use Only
RegisterLogin

PKM2-IN-3

CAT: 0804-HY-139667-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-139667-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PKM2-IN-3 is an inhibitor of PKM2 kinase with an IC50 value of 4.1 μM. PKM2-IN-3 exhibits an anti-neuroinflammatory effect by inhibiting PKM2-mediated glycolysis and NLRP3 activation[1].
CAS Number
2408841-19-8
UNSPSC
12352005
Target
Pyruvate Kinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pkm2-in-3.html
Purity
99.44
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
COC1=C2C(OCC/C(C2=O)=C\C3=CC=C(C=C3)CC)=CC(OC)=C1
Molecular Formula
C21H22O4
Molecular Weight
338.40
References & Citations
[1]Gao CL, et al. Synthesis and Target Identification of Benzoxepane Derivatives as Potential Anti-Neuroinflammatory Agents for Ischemic Stroke. Angew Chem Int Ed Engl. 2020;59 (6) :2429-2439.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-162071-01PKM2-IN-5
HY-178748PKM2-IN-12
HY-178441PKM2-IN-11
HY-170577PKM2-IN-8
HY-169567PKM2-IN-9
HY-103617-01PKM2-IN-1
HY-169883-01PKM2-IN-7
HY-172881PKM2-IN-10
HY-P702845-01PKM2, Human
HY-157913-01PKM2-IN-6

Alternative Products

CatalogName
BA8304-25PKM2-IN-3
T61504-01PKM2 activator 3
ant-009PKM2
PVT17455pCS2-PKM2-3×FLAG Plasmid
50295PKM2 (PKM2/Variant 1), His-tag
10R-11296PKM2 antibody
T204898-01PKM2-IN-9
T87217-01PKM2-IN-6
381414PKM2 discontinued

Popular Products