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PKM2-IN-6

CAT: 0931-T87217-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T87217-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
771467-00-6
Target
PKM, Apoptosis
Related Pathways
Apoptosis, Metabolism
Purity
0.9983
Bioactivity
PKM2-IN-6 (compound 7d) is an orally active PKM2 inhibitor (IC50=23 nM) capable of inducing apoptosis and G2 cell cycle arrest. It reduces PKM1 and PKM2 expression at the mRNA level, exhibits antitumour activity, and is suitable for investigating triple-negative breast cancer (TNBC) .
Smiles
N(C1=NC(C=2N3C(=NC2)C=CC=C3)=CS1)C4=C(OC)C=CC=C4
Molecular Formula
C17H14N4OS
Molecular Weight
322.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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