PKM2-IN-6

• Target :

  PKM|||Apoptosis

• Related Pathways :

  Apoptosis|||Metabolism

• Purity :

  0.9983

• Bioactivity :

  PKM2-IN-6 (compound 7d) is an orally active PKM2 inhibitor (IC50=23 nM) capable of inducing apoptosis and G2 cell cycle arrest. It reduces PKM1 and PKM2 expression at the mRNA level, exhibits antitumour activity, and is suitable for investigating triple-negative breast cancer (TNBC) .

• Smiles :

  N(C1=NC(C=2N3C(=NC2)C=CC=C3)=CS1)C4=C(OC)C=CC=C4

• Molecular Formula :

  C17H14N4OS

• Molecular Weight :

  322.38

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  771467-00-6