LK 11

CAT: 0804-HY-121318Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-121318Size:1 Each
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Description
LK-11 is a tropane derivative that inhibits the passive uptake of noradrenalin (NA) by hypothalamic synaptic vesicles in vitro, similar to cocaine[1].
CAS Number
[74143-01-4]
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lk-11.html
Smiles
CN1[C@@]2([H])C[C@@H](C[C@]1([H])CC2)OC(CCN3CCOCC3)=O
Molecular Formula
C15H26N2O3
Molecular Weight
282.38
References & Citations
[1]Zakusov V V, et al. Effect of some tropane derivatives on noradrenalin uptake by synaptic vesicles of the hypothalamus[J]. Bulletin of Experimental Biology and Medicine, 1976, 82: 1020-1022.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported