LK-60

• UNSPSC Description:

  LK-60 is a potent DprE1 inhibitor. LK-60 effectively inhibits the proliferation of Mycobacterium tuberculosis. LK-60 has good safety profiles to gut microbiota and human cells[1].

• Target Antigen:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/lk-60.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C1N=C(N2C(NC3=CC=CC(C(F)(F)F)=C3)=CC(C)=N2)NC(CC)=C1

• Molecular Weight:

  363.34

• References & Citations:

  [1]Yang L, et al. Discovery of N-(1-(6-Oxo-1,6-dihydropyrimidine)-pyrazole) Acetamide Derivatives as Novel Noncovalent DprE1 Inhibitors against Mycobacterium tuberculosis. J Med Chem. 2024 Jan 17.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported