LK-44

CAT: 0804-HY-155228Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-155228Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HCES2A-IN-2 (Compound 44) is an orally active human carboxylesterase 2 (hCES2A) inhibitor (IC50: 5.02 μM) . hCES2A-IN-2 improves Irinotecan (HY-16562) -induced delayed diarrhea[1].
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lk-44.html
Solubility
10 mM in DMSO
Smiles
CCCOC1=CC=C(C(/C(O2)=C/C3=CC(Cl)=C(OC(C)(C)C(O)=O)C=C3)=O)C2=C1
Molecular Formula
C22H21ClO6
Molecular Weight
416.85
References & Citations
[1]Yang Z, et al. Design, synthesis, and biological evaluation studies of novel carboxylesterase 2 inhibitors for the treatment of irinotecan-induced delayed diarrhea. Bioorg Chem. 2023 Sep;138:106625.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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