LK-732

• Description:

  LK-732 is a thrombin inhibitor with anti-thrombotic activity.LK-732 has a dose-dependent inhibition of hypercoagulability in the model, with an IC50 of 1.3 mg/kg. LK-732 can be used in cardiovascular and cerebrovascular research[1].

• UNSPSC:

  12352005

• Target:

  Thrombin

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/lk-732.html

• Smiles:

  O=C(N1CCCCCC1)N(CC2=CC(C(N)=N)=CC=C2)NS(=O)(C3=CC4=C(C=CC=C4)C=C3)=O

• Molecular Formula:

  C25H29N5O3S

• Molecular Weight:

  479.59

• References & Citations:

  [1]Peternel L, et al. Antithrombotic potential of new direct thrombin inhibitors built on the azaphenylalanine scaffold in two rat venous thrombosis models. Thromb Haemost. 2005 Mar;93 (3) :437-42.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [673485-33-1]