TS-002266

• Description :

  TS-002266 is a small molecule TUT4/7 inhibitor with anti-leukemic effects. TS-002266 is promising for research of cancers[1].

• CAS Number :

  [2702325-64-0]

• UNSPSC :

  12352005

• Target :

  DNA/RNA Synthesis

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ts-002266.html

• Purity :

  98.99

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  COC1=C(C(OC[C@H]2CCCN2C3=C(C=C4C(C(C(O)=O)=CN(C4=C3)C5=CC=C(N=C5)N6CC(C6)N(C)C)=O)Cl)=NC=C1)Cl

• Molecular Formula :

  C31H32Cl2N6O5

• Molecular Weight :

  639.53

• References & Citations :

  [1]Triboulet R, et al. Targeting the synthetic lethal relationship between FOCAD and TUT7 represents a potential therapeutic opportunity for TUT4/7 small molecule inhibitors in cancer. Mol Cancer Ther. 2024 Sep 5.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported