PRMT5-IN-34

• UNSPSC Description:

  PRMT5-IN-34 (Compound C) is an inhibitor of MTA-cooperative Protein arginine methyltransferase 5 (PRMT5/MAT)[1].

• Target Antigen:

  Histone Methyltransferase

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/prmt5-in-34.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC#CCN1CC[C@]2(C3=CC=C(C=C3C(N2CC4=CC5=C(N4)C=C(C(N)=N5)F)=O)F)C1=O

• Molecular Weight:

  435.43

• References & Citations:

  [1]James T et al. Methylthioadenosine (MTA)-cooperative protein arginine methyltransferase 5 (PRMT5) inhibitors for use in the treatment of cancer that is wild type MTAP gene silenced. World Intellectual Property Organization, WO2024038004 A1 2024-02-22

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported