BRD9 Degrader-2

• UNSPSC Description:

  BRD9 Degrader-2 (Compound B11) is a BRD9 degrader (DC50 ≤1.25 nM; Dmax≥75%). BRD9 Degrader-2 can be used for research of cancers[1].

• Target Antigen:

  E1/E2/E3 Enzyme; Epigenetic Reader Domain; Molecular Glues

• Type:

  Reference compound

• Related Pathways:

  Epigenetics;Metabolic Enzyme/Protease;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/brd9-degrader-2.html

• Smiles:

  N#C/C(C(N1CCC2=C(C1C)C=CC=C2CN3CCN(CC3)CC4=C(OC)C=C(C5=CN(C)C(C(C)=C5C)=O)C=C4OC)=O)=C\C6=NC(C(F)(F)F)=CS6

• Molecular Weight:

  760.87

• References & Citations:

  [1]David MCGARRY, et al. Compounds for targeted protein degradation. Patent. WO2024057021A1

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3033018-68-4