Products for Research Use Only
RegisterLogin

PRMT5-MTA-IN-1

CAT: 0804-HY-163799Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-163799Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PRMT5-MTA-IN-1 (Compound A9a) is an inhibitor for protein arginine methyltransferase PRMT5-MTA. PRMT5-MTA-IN-1 inhibits the proliferation of colorectal cancer cell HCT116 wildtype and MTAP del mutant, with an IC50 of 16 nM and 2.47 μM. PRMT5-MTA-IN-1 exhibits good liver microsomal stability and film permeability. PRMT5-MTA-IN-1 exhibits good pharmacokinetic characteristics in CD-1 mice[1].
CAS Number
3048425-88-0
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/prmt5-mta-in-1.html
Smiles
CC1=C(C(N)=NC2=CC(F)=C(C=C21)C(N([C@@H]3COC4=CC(C(F)(F)F)=CC=C43)C)=O)CO
Molecular Formula
C22H19F4N3O3
Molecular Weight
449.40
References & Citations
[1]Liu B et al., PRMT5-MTA inhibitors. CN118271307A.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PRMT5

Related Products

CatalogName
HY-176701PRMT5-MTA-IN-4
HY-176702PRMT5-MTA-IN-5
HY-174983PRMT5-MTA-IN-6
HY-172733PRMT5-MTA-IN-3
HY-162989PRMT5-MTA-IN-2
HY-172733SPRMT5-MTA-IN-3-d3
HY-126256PRMT5-IN-1
HY-173092PRMT5 ligand 1
HY-126256A-01PRMT5-IN-1 (hydrochloride)
HY-163434PRMT5/EGFR-IN-1

Alternative Products

CatalogName
GTR19262974-01PRMT5-MTA-IN-1
T201208-01PRMT5-MTA-IN-2
GTR19274723-01PRMT5-MTA-IN-7
GTR19263710-01PRMT5-MTA-IN-5
GTR19258702-01PRMT5-MTA-IN-3
T211767-01PRMT5-MTA-IN-6
T210750-01PRMT5-MTA-IN-4
PHY7394SMTA Antibody
TRC-M330650-100MG4-MTA
GTR19205073-01PRMT5-IN-1

Popular Products