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PRMT5 ligand 1

CAT: 0804-HY-173092Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-173092Size:1 Each
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Description
PRMT5 ligand 1 (compound 3) is the ligand for PRMT5 that can be used as target protein ligand for synthesis of PROTAC degrader MS4322.
CAS Number
1616393-25-9
UNSPSC
12352005
Target
Histone Methyltransferase; Ligands for Target Protein for PROTAC
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O[C@@H](CNC(C1=NC=NC(NC2CNC2)=C1)=O)CN3CCC4=C(C=CC=C4)C3
Molecular Formula
C20H26N6O2
Molecular Weight
382.46
References & Citations
[1]Shen Y, et al., Discovery of First-in-Class Protein Arginine Methyltransferase 5 (PRMT5) Degraders. J Med Chem. 2020 Sep 10;63 (17) :9977-9989.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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