Ac-ESMD-CHO

CAT: 0804-HY-P3234Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-P3234Size:1 Each

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Description

Ac-ESMD-CHO is an inhibitor of caspase-3 and caspase-7. Ac-ESMD-CHO inhibits proteolytic cleavage of the caspase-3 precursor peptide (CPP32) at the Glu-Ser-Met-Asp (ESMD) site[1][2].

CAS Number

191338-87-1

UNSPSC

12352209

Target

Casein Kinase

Type

Peptides

Related Pathways

Cell Cycle/DNA Damage; Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ac-esmd-cho.html

Solubility

10 mM in DMSO

Smiles

OC(C[C@@H](C=O)NC([C@H](CCSC)NC([C@H](CO)NC([C@@H](NC(C)=O)CCC(O)=O)=O)=O)=O)=O

Molecular Formula

C19H30N4O10S

Molecular Weight

506.53

References & Citations

[1]Hayashida M, et al. Cell death induction by CTL: perforin/granzyme B system dominantly acts for cell death induction in human hepatocellular carcinoma cells. Proc Soc Exp Biol Med. 2000 Nov;225 (2) :143-50.|[2]Agniswamy J, et al. Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis. FEBS J. 2007 Sep;274 (18) :4752-65.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Related Products

Catalog	Name
HY-113963-01	Ac-IETD-CHO
HY-P10146	Ac-LETD-CHO
HY-134567	Ac-VDVAD-CHO
HY-108312	Ac-VEID-CHO
HY-W011254	Ac-VAD-CHO
HY-136733	Ac-DNLD-CHO
HY-120019-01	Ac-YVAD-CHO
HY-P2374	Ac-DMQD-CHO
HY-P10241	Ac-LEHD-CHO
HY-P1001-01	Ac-DEVD-CHO

Alternative Products

Catalog	Name
MBS5821735	Ac-ESMD-CHO
ALX-260-043-M005	Ac-IETD-CHO
ALX-260-047-M001	Ac-AAVALLPAVLLALLAPYVAD-CHO
ALX-260-055-M005	Ac-WEHD-CHO
ALX-260-062-M001	Ac-VEID-CHO
TP3486-01	Ac-LETD-CHO
TP2534-01	Ac-LEHD-CHO
TP2527-01	Ac-DMQD-CHO
BUP00600-01	Ac-YVAD-CHO
MBS3841199-01	Ac-DEVD-CHO

Ac-ESMD-CHO

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