Ac-VAD-CHO

• UNSPSC Description:

  Ac-VAD-CHO (Ac-Val-Ala-Asp-CHO) is a pan-caspase inhibitor. Ac-VAD-CHO inhibits dissipation of MMP and cytochrome c release in hypoxia-exposed cells[1].

• Target Antigen:

  Caspase

• Type:

  Peptides

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ac-vad-cho.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC(C[C@@H](C=O)NC([C@H](C)NC([C@H](C(C)C)NC(C)=O)=O)=O)=O

• Molecular Weight:

  329.35

• References & Citations:

  [1]Jee-Youn Kim, et al. ROS-dependent caspase-9 activation in hypoxic cell death. FEBS Lett. 2003 Aug 14;549(1-3):94-8.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  147837-52-3