Ac-VAD-CHO

• Description :

  Ac-VAD-CHO (Ac-Val-Ala-Asp-CHO) is a pan-caspase inhibitor. Ac-VAD-CHO inhibits dissipation of MMP and cytochrome c release in hypoxia-exposed cells[1].

• Product Name Alternative :

  Ac-Val-Ala-Asp-CHO

• UNSPSC :

  12352209

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  Caspase

• Type :

  Peptides

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ac-vad-cho.html

• Solubility :

  10 mM in DMSO

• Smiles :

  OC(C[C@@H](C=O)NC([C@H](C)NC([C@H](C(C)C)NC(C)=O)=O)=O)=O

• Molecular Formula :

  C14H23N3O6

• Molecular Weight :

  329.35

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Jee-Youn Kim, et al. ROS-dependent caspase-9 activation in hypoxic cell death. FEBS Lett. 2003 Aug 14;549 (1-3) :94-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [147837-52-3]