Ac-DNLD-CHO

• UNSPSC Description:

  Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is a Caspase-3/7 inhibitor (IC50: 9.89, 245 nM respectively; Kiapp: 0.68, 55.7 nM respectively). Ac-DNLD-CHO can be used for research of caspase-mediated apoptosis diseases, such as neurodegenerative disorders and viral infection diseases[1].

• Target Antigen:

  Caspase

• Type:

  Peptides

• Related Pathways:

  Apoptosis

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/ac-dnld-cho.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N[C@@H](CC(C)C)C(N[C@H](C=O)CC(O)=O)=O)[C@H](CC(N)=O)NC([C@@H](NC(C)=O)CC(O)=O)=O

• Molecular Weight:

  501.49

• References & Citations:

  [1]Yoshimori A, et al. Structural and functional definition of the specificity of a novel caspase-3 inhibitor, Ac-DNLD-CHO. BMC Pharmacol. 2007 Jun 27;7:8.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  775289-20-8