Ac-LETD-CHO

• UNSPSC Description:

  Ac-LETD-CHO is a caspases 8 inhibitor. Ac-LETD-CHO has specific inhibition to casp-8 with an IC50 value of 6.71 nM. Ac-LETD-CHO can be used for the research of anticancer[1].

• Target Antigen:

  Caspase

• Type:

  Peptides

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ac-letd-cho.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(O)=O)C=O)=O)=O)=O)C

• Molecular Weight:

  502.52

• References & Citations:

  [1]Hu J, et al. MALDI-MS Patterning of Caspase Activities and Its Application in the Assessment of Drug Resistance. Angew Chem Int Ed Engl. 2016 Jun 1;55(23):6667-70.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported