BMS-354326

• Description :

  BMS-354326 is a tryptase inhibitor with an IC50 of 1.8 nM. BMS-354326 exhibits excellent selectivity against trypsin and most other related serine proteases. BMS-354326 can be used in the research of asthma and inflammatory diseases[1].

• UNSPSC :

  12352005

• Target :

  Ser/Thr Protease

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Inflammation/Immunology

• Smiles :

  O=C([C@H]([C@H]1CCC2CNCCC2)N(C(N3CCN(C(CCCCCC4=CC=CC=C4)=O)CC3)=O)C1=O)O

• Molecular Formula :

  C28H40N4O5

• Molecular Weight :

  512.64

• References & Citations :

  [1]Bisacchi GS, et al. Synthesis of potent and highly selective nonguanidine azetidinone inhibitors of human tryptase. Bioorg Med Chem Lett. 2004 May 3;14 (9) :2227-31.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [708258-16-6]