BMS-354326

CAT: 0804-HY-120624Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-120624Size:1 Each
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Description
BMS-354326 is a tryptase inhibitor with an IC50 of 1.8 nM. BMS-354326 exhibits excellent selectivity against trypsin and most other related serine proteases. BMS-354326 can be used in the research of asthma and inflammatory diseases[1].
CAS Number
[708258-16-6]
UNSPSC
12352005
Target
Ser/Thr Protease
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Smiles
O=C([C@H]([C@H]1CCC2CNCCC2)N(C(N3CCN(C(CCCCCC4=CC=CC=C4)=O)CC3)=O)C1=O)O
Molecular Formula
C28H40N4O5
Molecular Weight
512.64
References & Citations
[1]Bisacchi GS, et al. Synthesis of potent and highly selective nonguanidine azetidinone inhibitors of human tryptase. Bioorg Med Chem Lett. 2004 May 3;14 (9) :2227-31.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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