BMT-297376

• Description :

  BMT-297376, the optimized Linrodostat, is a potent IDO1 inhibitor[1].

• UNSPSC :

  12352005

• Target :

  Indoleamine 2,3-Dioxygenase (IDO)

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/bmt-297376.html

• Purity :

  99.14

• Solubility :

  DMSO : 100 mg/mL (ultrasonic) |Methanol : ≥ 100 mg/mL

• Smiles :

  FC(C1=C(OC)N=CC=C1[C@H]2CC[C@@](CC2)([H])[C@@H](CC)NC(C3=CN=C(OC)C=C3)=O)F

• Molecular Formula :

  C23H29F2N3O3

• Molecular Weight :

  433.49

• References & Citations :

  [1]Roshan Y. Nimje, et al. Development of a Stereoselective and Scalable Synthesis for the Potent Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor, BMT-297376; N- ((R) -1- ((cis) -4- (3- (Difluoromethyl) -2-methoxypyridin-4-yl) cyclohexyl) propyl) -6-methoxynicotinamide. Org. Process Res. Dev. 2021, 25, 7, 1680-1689.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2251031-81-7]