BMT-297376

• Description:

  BMT-297376, the optimized Linrodostat, is a potent IDO1 inhibitor[1].

• UNSPSC:

  12352005

• Target:

  Indoleamine 2,3-Dioxygenase (IDO)

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/bmt-297376.html

• Purity:

  99.14

• Solubility:

  DMSO : 100 mg/mL (ultrasonic) |Methanol : ≥ 100 mg/mL

• Smiles:

  FC (C1=C (OC) N=CC=C1[C@H]2CC[C@@] (CC2) ([H]) [C@@H] (CC) NC (C3=CN=C (OC) C=C3) =O) F

• Molecular Formula:

  C23H29F2N3O3

• Molecular Weight:

  433.49

• References & Citations:

  [1]Roshan Y. Nimje, et al. Development of a Stereoselective and Scalable Synthesis for the Potent Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor, BMT-297376; N- ((R) -1- ((cis) -4- (3- (Difluoromethyl) -2-methoxypyridin-4-yl) cyclohexyl) propyl) -6-methoxynicotinamide. Org. Process Res. Dev. 2021, 25, 7, 1680-1689.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2251031-81-7