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BMT-108908

CAT: 0804-HY-117467Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-117467Size:1 Each
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Description
BMT-108908 is a negative allosteric modulator with selective activity on the NR2B subtype of the NMDA receptor. BMT-108908 has been shown to damage cognition in research, affecting cognitive functions in multiple areas. BMT-108908 failed to show a significant impact on the γ wave power of the EEG in the experiment, but it had a significant inhibitory and enhancement effect on the β wave and δ wave power[1].
CAS Number
1801151-15-4
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bmt-108908.html
Smiles
O=C1[C@H](N2CCC(C3=CC=C(C=C3)O)CC2)CCN1CC4=CC=C(C=C4)F
Molecular Formula
C22H25FN2O2
Molecular Weight
368.44
References & Citations
[1]The qEEG Signature of Selective NMDA NR2B Negative Allosteric Modulators; A Potential Translational Biomarker for Drug Development
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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