BMT-046091

• Description:

  BMT-046091 is a selective inhibitor of adaptor-associated kinase 1 (AAK1) . BMT-046091 inhibits phosphorylation of the μ2 peptide by AAK1 with an IC50 value of 2.8 nM[1].

• UNSPSC:

  12352005

• Target:

  AAK1

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/bmt-046091.html

• Smiles:

  O=C1NC2=CC(OC[C@@H](N)CC(C)C)=CC=C2C3=CC=NC=C13

• Molecular Formula:

  C18H21N3O2

• Molecular Weight:

  311.38

• References & Citations:

  [1]Justin V Louis, et al. [3H]BMT-046091 a potent and selective radioligand to determine AAK1 distribution and target engagement. Neuropharmacology. 2017 May 15:118:167-174.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1551401-20-7]