BMT-046091

• Description :

  BMT-046091 is a selective inhibitor of adaptor-associated kinase 1 (AAK1) . BMT-046091 inhibits phosphorylation of the μ2 peptide by AAK1 with an IC50 value of 2.8 nM[1].

• UNSPSC :

  12352005

• Target :

  AAK1

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/bmt-046091.html

• Smiles :

  O=C1NC2=CC(OC[C@@H](N)CC(C)C)=CC=C2C3=CC=NC=C13

• Molecular Formula :

  C18H21N3O2

• Molecular Weight :

  311.38

• References & Citations :

  [1]Justin V Louis, et al. [3H]BMT-046091 a potent and selective radioligand to determine AAK1 distribution and target engagement. Neuropharmacology. 2017 May 15:118:167-174.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1551401-20-7]