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Lu 26-046

CAT: 0804-HY-120329Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120329Size:1 Each
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Description
Lu 26-046 is the agonist for muscarinic M1 receptor and M2 receptor and a weak antagonist for M3 receptor, with Ki of 0.51, 26 and 5 nM, respectively. Lu 26-046 exhibits specific stimulus property, that can be recognized by rats[1].
CAS Number
143756-51-8
UNSPSC
12352005
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/lu-26-046.html
Smiles
C#CCOC1=NSC2=C1CNC[C@H]2C
Molecular Formula
C10H12N2OS
Molecular Weight
208.28
References & Citations
[1]Arnt J, et al., Discriminative stimulus properties of the muscarinic receptor agonists Lu 26-046 and O-Me-THPO in rats: evidence for involvement of different muscarinic receptor subtypes. Eur J Pharmacol. 1992 Jul 21;218 (1) :159-69.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAChR1; mAChR2; mAChR3

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