CZL-046

• Description:

  CZL-046 (compund 29) is an oral p300 bromodomain inhibitor[1].

• UNSPSC:

  12352005

• Target:

  Epigenetic Reader Domain

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Smiles:

  O=C1N([C@@H](C[C@@H]1F)C2=NC3=CC(C4=C(ON=C4C)C)=CC=C3N2[C@H]5CC[C@@H](CC5)OC([2H])([2H])[2H])C6=CC(F)=C(C=C6)F

• Molecular Formula:

  C29H26D3F3N4O3

• Molecular Weight:

  541.58

• References & Citations:

  [1]Chen Z, et al. Discovery of CZL-046 with an (S) -3-Fluoropyrrolidin-2-one Scaffold as a p300 Bromodomain Inhibitor for the Treatment of Multiple Myeloma. J Med Chem. 2024 Oct 24;67 (20) :18606-18628.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  [3032444-02-0]