11β-HSD1-IN-7

• UNSPSC Description:

  11β-HSD1-IN-7 (compound c10a) is a 11β?HSD1 inhibitor with an IC50 value of 1.9 μM for human 11β?HSD1. 11β-HSD1-IN-7 can be used for the research of diabetes and cognitive decline[1].

• Target Antigen:

  11β-HSD

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/11β-hsd1-in-7.html

• Purity:

  99.98

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(C1=CC=CC=C1)C2=CC=C(C(F)(F)F)C=C2

• Molecular Weight:

  250.219

• References & Citations:

  [1]Naredo-Gonzalez G, et al. Non-invasive in vivo assessment of 11β-hydroxysteroid dehydrogenase type 1 activity by 19F-Magnetic Resonance Spectroscopy. Sci Rep. 2022 Sep 29;12(1):16268.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  728-86-9