11β-HSD1-IN-12

11β-HSD1-IN-12

• CAS Number: 872506-67-7
• UNSPSC Description: 11β-HSD1-IN-12 is a 11β-HSD1 inhibitor (Example 21 in reference patent). 11β-HSD1 regenerates active glucocorticoids from inactive forms and is important in regulating intracellular glucocorticoid concentration. 11β-HSD1-IN-12 can be used in the research of obesity and metabolic syndrome[1].
• Target Antigen: 11β-HSD
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/11β-hsd1-in-12.html
• Solubility: 10 mM in DMSO
• Smiles: O=C([C@@H]1CN(S(=O)(C2=CC=CC(Cl)=C2C)=O)CCC1)NC3CCCCC3
• Molecular Weight: 398.95
• References & Citations: [1]Wenqing Yao, et al. N-substituted piperidines and their use as pharrmaceuticals. Patent. US20060004049A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported