11β-HSD1-IN-12

• UNSPSC Description:

  11β-HSD1-IN-12 is a 11β-HSD1 inhibitor (Example 21 in reference patent). 11β-HSD1 regenerates active glucocorticoids from inactive forms and is important in regulating intracellular glucocorticoid concentration. 11β-HSD1-IN-12 can be used in the research of obesity and metabolic syndrome[1].

• Target Antigen:

  11β-HSD

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/11β-hsd1-in-12.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C([C@@H]1CN(S(=O)(C2=CC=CC(Cl)=C2C)=O)CCC1)NC3CCCCC3

• Molecular Weight:

  398.95

• References & Citations:

  [1]Wenqing Yao, et al. N-substituted piperidines and their use as pharrmaceuticals. Patent. US20060004049A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  872506-67-7